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Intra-articular delivery of tetramethylpyrazine microspheres with enhanced articular cavity retention for treating osteoarthritis

Tetramethylpyrazine (TMP) is a traditional Chinese herbal medicine with strong anti-inflammatory and cartilage protection activities, and thus a promising candidate for treating osteoarthritis. However, TMP is rapidly cleared from the joint cavity after intra-articular injection and requires multipl...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiuping, Shi, Yang, Zhang, Zhiyue, Yang, Zhenlei, Huang, Guihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shenyang Pharmaceutical University 2018
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032152/ https://www.ncbi.nlm.nih.gov/pubmed/32104396 http://dx.doi.org/10.1016/j.ajps.2017.12.007

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