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Three dimensional distribution of surfactant in microspheres revealed by synchrotron radiation X-ray microcomputed tomography

This study investigated the formulation mechanism of microspheres via internal surfactant distribution. Eudragit L100 based microspheres loaded with bovine serum albumin were prepared by solid in oil in oil emulsion solvent evaporation method using acetone and liquid paraffin system containing sucro...

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Detalles Bibliográficos
Autores principales: Wu, Li, Wang, Manli, Singh, Vikramjeet, Li, Haiyan, Guo, Zhen, Gui, Shuangying, York, Peter, Xiao, Tiqiao, Yin, Xianzhen, Zhang, Jiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032157/
https://www.ncbi.nlm.nih.gov/pubmed/32104343
http://dx.doi.org/10.1016/j.ajps.2017.02.001