Design and evaluation of an extended-release matrix tablet formulation; the combination of hypromellose acetate succinate and hydroxypropylcellulose

The purpose of this study was to develop an extended-release (ER) matrix tablet that shows robust dissolution properties able to account for the variability of pH and mechanical stress in the GI tract using a combination of enteric polymer and hydrophilic polymer. Hypromellose acetate succinate (HPM...

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Detalles Bibliográficos
Autores principales: Fukui, Sachiko, Yano, Hideki, Yada, Shuichi, Mikkaichi, Tsuyoshi, Minami, Hidemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032166/
https://www.ncbi.nlm.nih.gov/pubmed/32104324
http://dx.doi.org/10.1016/j.ajps.2016.11.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032166/
https://www.ncbi.nlm.nih.gov/pubmed/32104324
http://dx.doi.org/10.1016/j.ajps.2016.11.002

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