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Complex formulations, simple techniques: Can 3D printing technology be the Midas touch in pharmaceutical industry?

3D printing is a method of rapid prototyping and manufacturing in which materials are deposited onto one another in layers to produce a three-dimensional object. Although 3D printing was developed in the 1980s and the technology has found widespread industrial applications for production from automo...

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Autores principales: Lamichhane, Shrawani, Bashyal, Santosh, Keum, Taekwang, Noh, Gyubin, Seo, Jo Eun, Bastola, Rakesh, Choi, Jaewoong, Sohn, Dong Hwan, Lee, Sangkil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032174/
https://www.ncbi.nlm.nih.gov/pubmed/32104475
http://dx.doi.org/10.1016/j.ajps.2018.11.008
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author Lamichhane, Shrawani
Bashyal, Santosh
Keum, Taekwang
Noh, Gyubin
Seo, Jo Eun
Bastola, Rakesh
Choi, Jaewoong
Sohn, Dong Hwan
Lee, Sangkil
author_facet Lamichhane, Shrawani
Bashyal, Santosh
Keum, Taekwang
Noh, Gyubin
Seo, Jo Eun
Bastola, Rakesh
Choi, Jaewoong
Sohn, Dong Hwan
Lee, Sangkil
author_sort Lamichhane, Shrawani
collection PubMed
description 3D printing is a method of rapid prototyping and manufacturing in which materials are deposited onto one another in layers to produce a three-dimensional object. Although 3D printing was developed in the 1980s and the technology has found widespread industrial applications for production from automotive parts to machine tools, its application in pharmaceutical area is still limited. However, the potential of 3D printing in the pharmaceutical industry is now being recognized. The ability of 3D printing to produce medications to exact specifications tailored to the needs of individual patients has indicated the possibility of developing personalized medicines. The technology allows dosage forms to be precisely printed in various shapes, sizes and textures that are difficult to produce using traditional techniques. However, there are various challenges associated with the proper application of 3D printing in the pharmaceutical sector which should be overcome to exploit the scope of this technology. In this review, an overview is provided on the various 3D printing technologies used in fabrication of complex dosage forms along with their feasibility and limitations.
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spelling pubmed-70321742020-02-26 Complex formulations, simple techniques: Can 3D printing technology be the Midas touch in pharmaceutical industry? Lamichhane, Shrawani Bashyal, Santosh Keum, Taekwang Noh, Gyubin Seo, Jo Eun Bastola, Rakesh Choi, Jaewoong Sohn, Dong Hwan Lee, Sangkil Asian J Pharm Sci Review Article 3D printing is a method of rapid prototyping and manufacturing in which materials are deposited onto one another in layers to produce a three-dimensional object. Although 3D printing was developed in the 1980s and the technology has found widespread industrial applications for production from automotive parts to machine tools, its application in pharmaceutical area is still limited. However, the potential of 3D printing in the pharmaceutical industry is now being recognized. The ability of 3D printing to produce medications to exact specifications tailored to the needs of individual patients has indicated the possibility of developing personalized medicines. The technology allows dosage forms to be precisely printed in various shapes, sizes and textures that are difficult to produce using traditional techniques. However, there are various challenges associated with the proper application of 3D printing in the pharmaceutical sector which should be overcome to exploit the scope of this technology. In this review, an overview is provided on the various 3D printing technologies used in fabrication of complex dosage forms along with their feasibility and limitations. Shenyang Pharmaceutical University 2019-09 2019-02-14 /pmc/articles/PMC7032174/ /pubmed/32104475 http://dx.doi.org/10.1016/j.ajps.2018.11.008 Text en © 2019 Shenyang Pharmaceutical University. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Lamichhane, Shrawani
Bashyal, Santosh
Keum, Taekwang
Noh, Gyubin
Seo, Jo Eun
Bastola, Rakesh
Choi, Jaewoong
Sohn, Dong Hwan
Lee, Sangkil
Complex formulations, simple techniques: Can 3D printing technology be the Midas touch in pharmaceutical industry?
title Complex formulations, simple techniques: Can 3D printing technology be the Midas touch in pharmaceutical industry?
title_full Complex formulations, simple techniques: Can 3D printing technology be the Midas touch in pharmaceutical industry?
title_fullStr Complex formulations, simple techniques: Can 3D printing technology be the Midas touch in pharmaceutical industry?
title_full_unstemmed Complex formulations, simple techniques: Can 3D printing technology be the Midas touch in pharmaceutical industry?
title_short Complex formulations, simple techniques: Can 3D printing technology be the Midas touch in pharmaceutical industry?
title_sort complex formulations, simple techniques: can 3d printing technology be the midas touch in pharmaceutical industry?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032174/
https://www.ncbi.nlm.nih.gov/pubmed/32104475
http://dx.doi.org/10.1016/j.ajps.2018.11.008
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