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Influence of solvent mixtures on HPMCAS-celecoxib microparticles prepared by electrospraying

Hypromellose acetate succinate (HPMCAS) microparticles containing the poorly-water soluble drug celecoxib (CEL) were prepared by electrospraying intended for oral drug delivery. Various solvent mixtures with different solubility for CEL and HPMCAS were used to induce changes in the polymer structura...

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Detalles Bibliográficos
Autores principales:	Bohr, Adam, Wang, Yingya, Beck-Broichsitter, Moritz, Yang, Mingshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shenyang Pharmaceutical University 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032181/ https://www.ncbi.nlm.nih.gov/pubmed/32104432 http://dx.doi.org/10.1016/j.ajps.2018.01.007

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