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Amino functionalized chiral mesoporous silica nanoparticles for improved loading and release of poorly water-soluble drug

In the present paper, chiral mesoporous silica nano-cocoon (A-CMSN) functionalized with amino group was synthesized, and its loading and release of indomethacin (IMC), a poorly soluble drug, was studied. Due to the use of chiral anionic surfactants as a template, A-CMSN possessed 2D hexagonal nano-c...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Li, Chang, Fan, Na, Li, Jing, Zhang, Haotian, Shang, Lei, He, Zhonggui, Sun, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032221/
https://www.ncbi.nlm.nih.gov/pubmed/32104469
http://dx.doi.org/10.1016/j.ajps.2018.04.002