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Enhanced digestion inhibition and mucus penetration of F127-modified self-nanoemulsions for improved oral delivery()
Self-nanoemulsifying systems (SNEs) have excellent ability to improve the solubility of poorly water-soluble drugs (PWSD). However, SNEs are likely to be degraded in gastrointestinal (GIT) when their surface is recognized by lipase/co-lipase enzyme complex, resulting in rapid release and precipitati...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032245/ https://www.ncbi.nlm.nih.gov/pubmed/32104406 http://dx.doi.org/10.1016/j.ajps.2018.03.001 |