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A systematic in vitro investigation on poly-arginine modified nanostructured lipid carrier: Pharmaceutical characteristics, cellular uptake, mechanisms and cytotoxicity

The aim of the present study was to develop a poly-arginine modified nanostructured lipid carrier (R-NLC) by fusion-emulsification method and to test its pharmaceutical characteristics. The influence of R-NLC on A549 cells like cellular uptake and cytotoxicity was also appraised using unmodified NLC...

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Detalles Bibliográficos
Autores principales: Sun, Mingshuang, Gao, Yunyun, Zhu, Zhihong, Wang, Huixin, Han, Cuiyan, Yang, Xinggang, Pan, Weisan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032249/
https://www.ncbi.nlm.nih.gov/pubmed/32104313
http://dx.doi.org/10.1016/j.ajps.2016.07.007