Spray freeze drying of small nucleic acids as inhaled powder for pulmonary delivery

The therapeutic potential of small nucleic acids such as small interfering RNA (siRNA) to treat lung diseases has been successfully demonstrated in many in vivo studies. A major barrier to their clinical application is the lack of a safe and efficient inhaled formulation. In this study, spray freeze...

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Detalles Bibliográficos
Autores principales: Liang, Wanling, Chan, Alan Y.L., Chow, Michael Y.T., Lo, Fiona F.K., Qiu, Yingshan, Kwok, Philip C.L., Lam, Jenny K.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032260/
https://www.ncbi.nlm.nih.gov/pubmed/32104389
http://dx.doi.org/10.1016/j.ajps.2017.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032260/
https://www.ncbi.nlm.nih.gov/pubmed/32104389
http://dx.doi.org/10.1016/j.ajps.2017.10.002

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