The PAR2 signal peptide prevents premature receptor cleavage and activation

Unlike closely related GPCRs, protease-activated receptors (PAR1, PAR2, PAR3, and PAR4) have a predicted signal peptide at their N-terminus, which is encoded by a separate exon, suggesting that the signal peptides of PARs may serve an important and unique function, specific for PARs. In this report,...

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Detalles Bibliográficos
Autores principales: Liu, Belinda, Lee, Grace, Wu, Jiejun, Deming, Janise, Kuei, Chester, Harrington, Anthony, Wang, Lien, Towne, Jennifer, Lovenberg, Timothy, Liu, Changlu, Sun, Siquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032737/
https://www.ncbi.nlm.nih.gov/pubmed/32078628
http://dx.doi.org/10.1371/journal.pone.0222685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032737/
https://www.ncbi.nlm.nih.gov/pubmed/32078628
http://dx.doi.org/10.1371/journal.pone.0222685

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