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Development of a PC12 Cell Based Assay for Screening Catechol-O-methyltransferase Inhibitors

[Image: see text] The male rat adrenal pheochromocytoma cell-derived PC12 cell line can synthesize and release catecholamine neurotransmitters, and it has been widely used as a model system in cell biology and toxicology research. Catechol-O-methyltransferase (COMT) is involved in the inactivation o...

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Detalles Bibliográficos
Autores principales:	Zhang, Gongliang, Buchler, Ingrid P., DePasquale, Michael, Wormald, Michael, Liao, Gangling, Wei, Huijun, Barrow, James C., Carr, Gregory V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032882/ https://www.ncbi.nlm.nih.gov/pubmed/31491076 http://dx.doi.org/10.1021/acschemneuro.9b00395

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