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TGF-β1 accelerates the hepatitis B virus X-induced malignant transformation of hepatic progenitor cells by upregulating miR-199a-3p

Increasing evidence has suggested that liver cancer arises partially from transformed hepatic progenitor cells (HPCs). However, the detailed mechanisms underlying HPC transformation are poorly understood. In this study, we provide evidence linking the coexistence of hepatitis B virus X protein (HBx)...

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Detalles Bibliográficos
Autores principales:	Dong, Ke-shuai, Chen, Yan, Yang, Guang, Liao, Zhi-bin, Zhang, Hong-wei, Liang, Hui-fang, Chen, Xiao-ping, Dong, Han-hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033045/ https://www.ncbi.nlm.nih.gov/pubmed/31740785 http://dx.doi.org/10.1038/s41388-019-1107-9

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