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Relaxed sequence constraints favor mutational freedom in idiosyncratic metazoan mitochondrial tRNAs
Metazoan complexity and life-style depend on the bioenergetic potential of mitochondria. However, higher aerobic activity and genetic drift impose strong mutation pressure and risk of irreversible fitness decline in mitochondrial (mt)DNA-encoded genes. Bilaterian mitochondria-encoded tRNA genes, key...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033119/ https://www.ncbi.nlm.nih.gov/pubmed/32080176 http://dx.doi.org/10.1038/s41467-020-14725-y |