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Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase

Core-fucosylation is an essential biological modification by which a fucose is transferred from GDP-β-L-fucose to the innermost N-acetylglucosamine residue of N-linked glycans. A single human enzyme α1,6-fucosyltransferase (FUT8) is the only enzyme responsible for this modification via the addition...

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Detalles Bibliográficos
Autores principales:	García-García, Ana, Ceballos-Laita, Laura, Serna, Sonia, Artschwager, Raik, Reichardt, Niels C., Corzana, Francisco, Hurtado-Guerrero, Ramon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033129/ https://www.ncbi.nlm.nih.gov/pubmed/32080177 http://dx.doi.org/10.1038/s41467-020-14794-z

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