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Vaginal microbiota diverges in sows with low and high reproductive performance after porcine reproductive and respiratory syndrome vaccination

Previous studies have demonstrated evidence for a relationship between the vaginal microbiome and reproductive performance, suggesting the vaginal microbiota may serve as a tool to predict farrowing outcomes in commercial pigs. In this study, we compared the vaginal microbiome in sows with low and h...

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Autores principales: Sanglard, L. P., Schmitz-Esser, S., Gray, K. A., Linhares, D. C. L., Yeoman, C. J., Dekkers, J. C. M., Niederwerder, M. C., Serão, N. V. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033195/
https://www.ncbi.nlm.nih.gov/pubmed/32080317
http://dx.doi.org/10.1038/s41598-020-59955-8
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author Sanglard, L. P.
Schmitz-Esser, S.
Gray, K. A.
Linhares, D. C. L.
Yeoman, C. J.
Dekkers, J. C. M.
Niederwerder, M. C.
Serão, N. V. L.
author_facet Sanglard, L. P.
Schmitz-Esser, S.
Gray, K. A.
Linhares, D. C. L.
Yeoman, C. J.
Dekkers, J. C. M.
Niederwerder, M. C.
Serão, N. V. L.
author_sort Sanglard, L. P.
collection PubMed
description Previous studies have demonstrated evidence for a relationship between the vaginal microbiome and reproductive performance, suggesting the vaginal microbiota may serve as a tool to predict farrowing outcomes in commercial pigs. In this study, we compared the vaginal microbiome in sows with low and high farrowing performance and used it to classify animals with contrasting reproductive outcomes in commercial sows following immune challenge with porcine respiratory and reproductive syndrome (PRRS) vaccination. Eighteen microbes were differentially abundant (q-value < 0.05) between the Low and High farrowing performance groups. Among them, Campylobacter, Bacteroides, Porphyromonas, Lachnospiraceae unclassified, Prevotella, and Phascolarctobacterium were also selected in the discriminant and linear regression analyses, and could be used as potential biomarkers for reproductive outcomes. The correct classification rate in the two groups was 100%. In conclusion, this study demonstrates that vaginal microbiota collected after PRRS vaccination could be potentially used to classify sows into having low or high farrowing performance in commercial herds.
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spelling pubmed-70331952020-02-28 Vaginal microbiota diverges in sows with low and high reproductive performance after porcine reproductive and respiratory syndrome vaccination Sanglard, L. P. Schmitz-Esser, S. Gray, K. A. Linhares, D. C. L. Yeoman, C. J. Dekkers, J. C. M. Niederwerder, M. C. Serão, N. V. L. Sci Rep Article Previous studies have demonstrated evidence for a relationship between the vaginal microbiome and reproductive performance, suggesting the vaginal microbiota may serve as a tool to predict farrowing outcomes in commercial pigs. In this study, we compared the vaginal microbiome in sows with low and high farrowing performance and used it to classify animals with contrasting reproductive outcomes in commercial sows following immune challenge with porcine respiratory and reproductive syndrome (PRRS) vaccination. Eighteen microbes were differentially abundant (q-value < 0.05) between the Low and High farrowing performance groups. Among them, Campylobacter, Bacteroides, Porphyromonas, Lachnospiraceae unclassified, Prevotella, and Phascolarctobacterium were also selected in the discriminant and linear regression analyses, and could be used as potential biomarkers for reproductive outcomes. The correct classification rate in the two groups was 100%. In conclusion, this study demonstrates that vaginal microbiota collected after PRRS vaccination could be potentially used to classify sows into having low or high farrowing performance in commercial herds. Nature Publishing Group UK 2020-02-20 /pmc/articles/PMC7033195/ /pubmed/32080317 http://dx.doi.org/10.1038/s41598-020-59955-8 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Sanglard, L. P.
Schmitz-Esser, S.
Gray, K. A.
Linhares, D. C. L.
Yeoman, C. J.
Dekkers, J. C. M.
Niederwerder, M. C.
Serão, N. V. L.
Vaginal microbiota diverges in sows with low and high reproductive performance after porcine reproductive and respiratory syndrome vaccination
title Vaginal microbiota diverges in sows with low and high reproductive performance after porcine reproductive and respiratory syndrome vaccination
title_full Vaginal microbiota diverges in sows with low and high reproductive performance after porcine reproductive and respiratory syndrome vaccination
title_fullStr Vaginal microbiota diverges in sows with low and high reproductive performance after porcine reproductive and respiratory syndrome vaccination
title_full_unstemmed Vaginal microbiota diverges in sows with low and high reproductive performance after porcine reproductive and respiratory syndrome vaccination
title_short Vaginal microbiota diverges in sows with low and high reproductive performance after porcine reproductive and respiratory syndrome vaccination
title_sort vaginal microbiota diverges in sows with low and high reproductive performance after porcine reproductive and respiratory syndrome vaccination
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033195/
https://www.ncbi.nlm.nih.gov/pubmed/32080317
http://dx.doi.org/10.1038/s41598-020-59955-8
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