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Annexin A1 accounts for an anti-inflammatory binding target of sesamin metabolites
Sesamin [(7α,7′α,8α,8′α)-3,4:3′,4′-bis(methylenedioxy)-7,9′:7′,9-diepoxylignane] is a major lignan in sesame seeds. Sesamin is converted to the catechol metabolite, SC1 [(7α,7′α,8α,8′α)-3′,4′-methylenedioxy-7,9′:7′,9-diepoxylignane-3,4-diol] with anti-inflammatory effects after oral administration....
Autores principales: | Kabe, Yasuaki, Takemoto, Daisuke, Kanai, Ayaka, Hirai, Miwa, Ono, Yoshiko, Akazawa, Sota, Horikawa, Manabu, Kitagawa, Yoshinori, Handa, Hiroshi, Rogi, Tomohiro, Shibata, Hiroshi, Suematsu, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033200/ https://www.ncbi.nlm.nih.gov/pubmed/32133417 http://dx.doi.org/10.1038/s41538-020-0064-6 |
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