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Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers

Epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3) have been investigated as triple-negative breast cancer (TNBC) biomarkers. Reduced EGFR levels can be compensated by increases in HER3; thus, assaying EGFR and HER3 together may improve prognostic value. In a...

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Detalles Bibliográficos
Autores principales: Ogden, Angela, Bhattarai, Shristi, Sahoo, Bikram, Mongan, Nigel P., Alsaleem, Mansour, Green, Andrew R., Aleskandarany, Mohammed, Ellis, Ian O., Pattni, Sonal, Li, Xiaoxian (Bill), Moreno, Carlos S., Krishnamurti, Uma, Janssen, Emiel A., Jonsdottir, Kristin, Rakha, Emad, Rida, Padmashree, Aneja, Ritu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033213/
https://www.ncbi.nlm.nih.gov/pubmed/32080212
http://dx.doi.org/10.1038/s41598-020-59514-1