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Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers
Epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3) have been investigated as triple-negative breast cancer (TNBC) biomarkers. Reduced EGFR levels can be compensated by increases in HER3; thus, assaying EGFR and HER3 together may improve prognostic value. In a...
Autores principales: | Ogden, Angela, Bhattarai, Shristi, Sahoo, Bikram, Mongan, Nigel P., Alsaleem, Mansour, Green, Andrew R., Aleskandarany, Mohammed, Ellis, Ian O., Pattni, Sonal, Li, Xiaoxian (Bill), Moreno, Carlos S., Krishnamurti, Uma, Janssen, Emiel A., Jonsdottir, Kristin, Rakha, Emad, Rida, Padmashree, Aneja, Ritu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033213/ https://www.ncbi.nlm.nih.gov/pubmed/32080212 http://dx.doi.org/10.1038/s41598-020-59514-1 |
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