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Dual functional highly luminescence B, N Co-doped carbon nanodots as nanothermometer and Fe(3+)/Fe(2+) sensor

Dual functional fluorescence nanosensors have many potential applications in biology and medicine. Monitoring temperature with higher precision at localized small length scales or in a nanocavity is a necessity in various applications. As well as the detection of biologically interesting metal ions...

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Autores principales: Mohammed, Lazo Jazaa, Omer, Khalid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033239/
https://www.ncbi.nlm.nih.gov/pubmed/32080282
http://dx.doi.org/10.1038/s41598-020-59958-5
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author Mohammed, Lazo Jazaa
Omer, Khalid M.
author_facet Mohammed, Lazo Jazaa
Omer, Khalid M.
author_sort Mohammed, Lazo Jazaa
collection PubMed
description Dual functional fluorescence nanosensors have many potential applications in biology and medicine. Monitoring temperature with higher precision at localized small length scales or in a nanocavity is a necessity in various applications. As well as the detection of biologically interesting metal ions using low-cost and sensitive approach is of great importance in bioanalysis. In this paper, we describe the preparation of dual-function highly fluorescent B, N-co-doped carbon nanodots (CDs) that work as chemical and thermal sensors. The CDs emit blue fluorescence peaked at 450 nm and exhibit up to 70% photoluminescence quantum yield with showing excitation-independent fluorescence. We also show that water-soluble CDs display temperature-dependent fluorescence and can serve as highly sensitive and reliable nanothermometers with a thermo-sensitivity 1.8% °C(−1), and wide range thermo-sensing between 0–90 °C with excellent recovery. Moreover, the fluorescence emission of CDs are selectively quenched after the addition of Fe(2+) and Fe(3+) ions while show no quenching with adding other common metal cations and anions. The fluorescence emission shows a good linear correlation with concentration of Fe(2+) and Fe(3+) (R(2) = 0.9908 for Fe(2+) and R(2) = 0.9892 for Fe(3+)) with a detection limit of of 80.0 ± 0.5 nM for Fe(2+) and 110.0 ± 0.5 nM for Fe(3+). Considering the high quantum yield and selectivity, CDs are exploited to design a nanoprobe towards iron detection in a biological sample. The fluorimetric assay is used to detect Fe(2+) in iron capsules and total iron in serum samples successfully.
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spelling pubmed-70332392020-02-28 Dual functional highly luminescence B, N Co-doped carbon nanodots as nanothermometer and Fe(3+)/Fe(2+) sensor Mohammed, Lazo Jazaa Omer, Khalid M. Sci Rep Article Dual functional fluorescence nanosensors have many potential applications in biology and medicine. Monitoring temperature with higher precision at localized small length scales or in a nanocavity is a necessity in various applications. As well as the detection of biologically interesting metal ions using low-cost and sensitive approach is of great importance in bioanalysis. In this paper, we describe the preparation of dual-function highly fluorescent B, N-co-doped carbon nanodots (CDs) that work as chemical and thermal sensors. The CDs emit blue fluorescence peaked at 450 nm and exhibit up to 70% photoluminescence quantum yield with showing excitation-independent fluorescence. We also show that water-soluble CDs display temperature-dependent fluorescence and can serve as highly sensitive and reliable nanothermometers with a thermo-sensitivity 1.8% °C(−1), and wide range thermo-sensing between 0–90 °C with excellent recovery. Moreover, the fluorescence emission of CDs are selectively quenched after the addition of Fe(2+) and Fe(3+) ions while show no quenching with adding other common metal cations and anions. The fluorescence emission shows a good linear correlation with concentration of Fe(2+) and Fe(3+) (R(2) = 0.9908 for Fe(2+) and R(2) = 0.9892 for Fe(3+)) with a detection limit of of 80.0 ± 0.5 nM for Fe(2+) and 110.0 ± 0.5 nM for Fe(3+). Considering the high quantum yield and selectivity, CDs are exploited to design a nanoprobe towards iron detection in a biological sample. The fluorimetric assay is used to detect Fe(2+) in iron capsules and total iron in serum samples successfully. Nature Publishing Group UK 2020-02-20 /pmc/articles/PMC7033239/ /pubmed/32080282 http://dx.doi.org/10.1038/s41598-020-59958-5 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Mohammed, Lazo Jazaa
Omer, Khalid M.
Dual functional highly luminescence B, N Co-doped carbon nanodots as nanothermometer and Fe(3+)/Fe(2+) sensor
title Dual functional highly luminescence B, N Co-doped carbon nanodots as nanothermometer and Fe(3+)/Fe(2+) sensor
title_full Dual functional highly luminescence B, N Co-doped carbon nanodots as nanothermometer and Fe(3+)/Fe(2+) sensor
title_fullStr Dual functional highly luminescence B, N Co-doped carbon nanodots as nanothermometer and Fe(3+)/Fe(2+) sensor
title_full_unstemmed Dual functional highly luminescence B, N Co-doped carbon nanodots as nanothermometer and Fe(3+)/Fe(2+) sensor
title_short Dual functional highly luminescence B, N Co-doped carbon nanodots as nanothermometer and Fe(3+)/Fe(2+) sensor
title_sort dual functional highly luminescence b, n co-doped carbon nanodots as nanothermometer and fe(3+)/fe(2+) sensor
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033239/
https://www.ncbi.nlm.nih.gov/pubmed/32080282
http://dx.doi.org/10.1038/s41598-020-59958-5
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