Leptin receptor–expressing cells represent a distinct subpopulation of notochord-derived cells and are essential for disc homoeostasis

BACKGROUND/OBJECTIVE: Intervertebral disc degeneration (IDD) remains to be an intractable clinical challenge. Although IDD is characterised by loss of notochordal cells (NCs) and dysfunction of nucleus pulposus (NP) cells, little is known about the origin, heterogeneity, fate and maintenance of NCs...

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Detalles Bibliográficos
Autores principales: Gao, Bo, Yin, Jinhua, Xu, Xiaolong, Fan, Jing, Wang, Di, Zheng, Chao, Lu, Weiguang, Cheng, Pengzhen, Sun, Jicheng, Wang, Dong, Li, Lu, Zhou, Bo O., Yang, Liu, Luo, Zhuojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033302/
https://www.ncbi.nlm.nih.gov/pubmed/32110508
http://dx.doi.org/10.1016/j.jot.2019.11.005

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