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Inhibitory effect of Korean Red Ginseng extract on DNA damage response and apoptosis in Helicobacter pylori–infected gastric epithelial cells

BACKGROUND: Helicobacter pylori increases reactive oxygen species (ROS) and induces oxidative DNA damage and apoptosis in gastric epithelial cells. DNA damage activates DNA damage response (DDR) which includes ataxia-telangiectasia-mutated (ATM) activation. ATM increases alternative reading frame (A...

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Detalles Bibliográficos
Autores principales: Kang, Hyunju, Lim, Joo Weon, Kim, Hyeyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033323/
https://www.ncbi.nlm.nih.gov/pubmed/32148392
http://dx.doi.org/10.1016/j.jgr.2018.08.003