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Lipid Peroxidation Plays an Important Role in Chemotherapeutic Effects of Temozolomide and the Development of Therapy Resistance in Human Glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most malignant primary brain tumor. Relapse occurs regularly, and the clinical behavior seems to be due to a therapy-resistant subpopulation of glioma-initiating cells that belong to the group of cancer stem cells. Aldehyde dehydrogenase (ALDH) has been identifi...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Wu, Yang, Mayer, Karoline, von Rosenstiel, Charlotte, Schecker, Johannes, Baur, Sandra, Würstle, Sylvia, Liesche-Starnecker, Friederike, Gempt, Jens, Schlegel, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033364/
https://www.ncbi.nlm.nih.gov/pubmed/32087559
http://dx.doi.org/10.1016/j.tranon.2020.100748