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Prediction and visualization of CYP2D6 genotype-based phenotype using clustering algorithms

This study focused on the role of cytochrome P450 2D6 (CYP2D6) genotypes to predict phenotypes in the metabolism of dextromethorphan. CYP2D6 genotypes and metabolic ratios (MRs) of dextromethorphan were determined in 201 Koreans. Unsupervised clustering algorithms, hierarchical and k-means clusterin...

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Detalles Bibliográficos
Autores principales:	Kim, Eun-Young, Shin, Sang-Goo, Shin, Jae-Gook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Clinical Pharmacology and Therapeutics 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033374/ https://www.ncbi.nlm.nih.gov/pubmed/32095466 http://dx.doi.org/10.12793/tcp.2017.25.3.147

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