Cargando…

Inhibition of indoxyl sulfate-induced intrarenal renin-angiotensin system activation: targeting the aryl hydrocarbon receptor

Indoxyl sulfate, a protein-bound uremic toxin, leads to CKD (chronic kidney disease) progression and its complications through the activation of AhR (aryl hydrocarbon receptor) and RAS (renin-angiotensin system). Inhibition of these pathways may slow the development of CKD and CKD-associated complic...

Descripción completa

Detalles Bibliográficos
Autor principal:	Akbar, Muhammad Firman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Clinical Pharmacology and Therapeutics 2017
Materias:	News
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033375/ https://www.ncbi.nlm.nih.gov/pubmed/32095460 http://dx.doi.org/10.12793/tcp.2017.25.3.114

Ejemplares similares

Aryl Hydrocarbon Receptor Inhibition Restores Indoxyl Sulfate-Mediated Endothelial Dysfunction in Rat Aortic Rings
por: Nguyen, Cindy, et al.
Publicado: (2022)

Podocyte Injury Caused by Indoxyl Sulfate, a Uremic Toxin and Aryl-Hydrocarbon Receptor Ligand
por: Ichii, Osamu, et al.
Publicado: (2014)

Resveratrol Rescue Indoxyl Sulfate-Induced Deterioration of Osteoblastogenesis via the Aryl Hydrocarbon Receptor /MAPK Pathway
por: Liu, Wen-Chih, et al.
Publicado: (2020)

Concentration and Duration of Indoxyl Sulfate Exposure Affects Osteoclastogenesis by Regulating NFATc1 via Aryl Hydrocarbon Receptor
por: Liu, Wen-Chih, et al.
Publicado: (2020)

Aryl Hydrocarbon Receptor Activation and Tissue Factor Induction by Fluid Shear Stress and Indoxyl Sulfate in Endothelial Cells
por: Lano, Guillaume, et al.
Publicado: (2020)

Role of Resveratrol on Indoxyl Sulfate-Induced Endothelial Hyperpermeability via Aryl Hydrocarbon Receptor (AHR)/Src-Dependent Pathway
por: Assefa, Eskedar Getachew, et al.
Publicado: (2019)

The Relationship between the Intrarenal Dopamine System and Intrarenal Renin-angiotensin System Depending on the Renal Function
por: Matsuyama, Takashi, et al.
Publicado: (2018)

The Adipose Renin-Angiotensin System Modulates Systemic Markers of Insulin Sensitivity and Activates the Intrarenal Renin-Angiotensin System
por: Kim, Suyeon, et al.
Publicado: (2006)

Involvement of the Intrarenal Renin-Angiotensin System in Experimental Models of Glomerulonephritis
por: Urushihara, Maki, et al.
Publicado: (2012)

Intrarenal Renin-Angiotensin-System Dysregulation after Kidney Transplantation
por: Kovarik, Johannes J., et al.
Publicado: (2019)

Chronotherapy with a Renin-angiotensin System Inhibitor Ameliorates Renal Damage by Suppressing Intrarenal Renin-angiotensin System Activation
por: Aoki, Taro, et al.
Publicado: (2020)

Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease
por: Saigusa, Takamitsu, et al.
Publicado: (2015)

Circulating and intrarenal renin–angiotensin systems in healthy men and nonpregnant women
por: Pringle, Kirsty G, et al.
Publicado: (2015)

Angiotensin II Receptor Blocker Attenuates Intrarenal Renin-Angiotensin-System and Podocyte Injury in Rats with Myocardial Infarction
por: Wen, Zhu-zhi, et al.
Publicado: (2013)

JAK-STAT and the renin-angiotensin system: The role of the JAK-STAT pathway in blood pressure and intrarenal renin-angiotensin system regulation
por: Satou, Ryousuke, et al.
Publicado: (2012)

Intrarenal renin–angiotensin system activation and macrophage infiltrations in pediatric chronic glomerulonephritis
por: Hattori, Tomoki, et al.
Publicado: (2023)

Indoxyl Sulfate Promotes Macrophage IL-1β Production by Activating Aryl Hydrocarbon Receptor/NF-κ/MAPK Cascades, but the NLRP3 inflammasome Was Not Activated
por: Wakamatsu, Takuya, et al.
Publicado: (2018)

Preventing germ cell death by inactivating aryl hydrocarbon receptor (AHR)
por: Esakky, P, et al.
Publicado: (2016)

Characterization of the intrarenal renin‐angiotensin system in cats with naturally occurring chronic kidney disease
por: Lourenço, Bianca N., et al.
Publicado: (2022)

Aryl Hydrocarbon Receptor Ligands Indoxyl 3-sulfate and Indole-3-carbinol Inhibit FMS-like Tyrosine Kinase 3 Ligand-induced Bone Marrow-derived plasmacytoid Dendritic Cell Differentiation
por: Hwang, Won-Bhin, et al.
Publicado: (2018)

New Frontiers in the Intrarenal Renin-Angiotensin System: A Critical Review of Classical and New Paradigms
por: Zhuo, Jia L., et al.
Publicado: (2013)

The Intrarenal Renin-angiotensin System Is Activated Immediately after Kidney Donation in Kidney Transplant Donors
por: Ohashi, Naro, et al.
Publicado: (2018)

Effect of intrarenal renin-angiotensin-aldosterone system on renal function in patients after cardiac surgery
por: Niu, Peiyuan, et al.
Publicado: (2022)

Effect of a SGLT2 inhibitor on the systemic and intrarenal renin–angiotensin system in subtotally nephrectomized rats
por: Li, Lei, et al.
Publicado: (2017)

Foe and friend in the COVID-19-associated acute kidney injury: an insight on intrarenal renin-angiotensin system: Intrarenal RAS in COVID-19-associated AKI
por: Xu, Chuanming, et al.
Publicado: (2021)

H(2)S Inhibits Hyperglycemia-Induced Intrarenal Renin-Angiotensin System Activation via Attenuation of Reactive Oxygen Species Generation
por: Xue, Hong, et al.
Publicado: (2013)

Indoxyl Sulfate, a Uremic Endotheliotoxin
por: Lano, Guillaume, et al.
Publicado: (2020)

Molecular Mechanisms Involved in Intrarenal Renin-Angiotensin and Alternative Pathways in Diabetic Nephropathy - A Review
por: Bahreini, Elham, et al.
Publicado: (2021)

Indoxyl Sulfate-Induced Activation of (Pro)renin Receptor Promotes Cell Proliferation and Tissue Factor Expression in Vascular Smooth Muscle Cells
por: Yisireyili, Maimaiti, et al.
Publicado: (2014)

Intrarenal Renin Angiotensin System Imbalance During Postnatal Life Is Associated With Increased Microvascular Density in the Mature Kidney
por: Dalmasso, Carolina, et al.
Publicado: (2020)

Tiliroside Protects against Lipopolysaccharide-Induced Acute Kidney Injury via Intrarenal Renin–Angiotensin System in Mice
por: Yi, Xiaoli, et al.
Publicado: (2023)

The relationship of indoxyl sulfate and p-cresyl sulfate with target cardiovascular proteins in hemodialysis patients
por: Wu, Ping-Hsun, et al.
Publicado: (2021)

Addition of hydrochlorothiazide to angiotensin receptor blocker therapy can achieve a lower sodium balance with no acceleration of intrarenal renin angiotensin system in patients with chronic kidney disease
por: Fuwa, Daisuke, et al.
Publicado: (2016)

Indoxyl Sulfate—Review of Toxicity and Therapeutic Strategies
por: Leong, Sheldon C., et al.
Publicado: (2016)

Indoxyl sulfate impairs valsartan-induced neovascularization()
por: Kuo, Ko-Lin, et al.
Publicado: (2020)

Toxic Effects of Indoxyl Sulfate on Osteoclastogenesis and Osteoblastogenesis
por: Shyu, Jia-Fwu, et al.
Publicado: (2021)

The Aryl Hydrocarbon Receptor and the Nervous System
por: Juricek, Ludmila, et al.
Publicado: (2018)

Uremic Toxins Induce Kidney Fibrosis by Activating Intrarenal Renin–Angiotensin–Aldosterone System Associated Epithelial-to-Mesenchymal Transition
por: Sun, Chiao-Yin, et al.
Publicado: (2012)

Immunohistochemical expression of intrarenal renin angiotensin system components in response to tempol in rats fed a high salt diet
por: Cao, Gabriel, et al.
Publicado: (2017)

Gut microbiota dysbiosis-induced activation of the intrarenal renin–angiotensin system is involved in kidney injuries in rat diabetic nephropathy
por: Lu, Chen-chen, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_81ti56tem817h4iiqbqgd0pmfl