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Malnutrition Decreases Antibody Secreting Cell Numbers Induced by an Oral Attenuated Human Rotavirus Vaccine in a Human Infant Fecal Microbiota Transplanted Gnotobiotic Pig Model
Human rotavirus (HRV) is a leading cause of morbidity and mortality in children, especially in developing countries. Malnutrition is prevalent in these countries, which may contribute to the decreased oral vaccine efficacy, posing a concern for global health. Neonatal gnotobiotic (Gn) pigs closely r...
Autores principales: | Michael, Husheem, Langel, Stephanie N., Miyazaki, Ayako, Paim, Francine C., Chepngeno, Juliet, Alhamo, Moyasar A., Fischer, David D., Srivastava, Vishal, Kathayat, Dipak, Deblais, Loic, Rajashekara, Gireesh, Saif, Linda J., Vlasova, Anastasia N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033455/ https://www.ncbi.nlm.nih.gov/pubmed/32117313 http://dx.doi.org/10.3389/fimmu.2020.00196 |
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