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Comparative pharmacokinetic and tolerability evaluation of two simvastatin 20 mg formulations in healthy Korean male volunteers

Simvastatin is used to reduce plasma cholesterol by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and is primarily used to treat hypercholesterolemia. This study was conducted to assess the bioequivalence between the generic formulation of simvastatin 20 mg and the branded for...

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Detalles Bibliográficos
Autores principales:	Moon, Seol Ju, Lee, SeungHwan, Jang, Kyungho, Yu, Kyung-Sang, Yim, Sung-Vin, Kim, Bo-Hyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Clinical Pharmacology and Therapeutics 2017
Materias:	BE Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033535/ https://www.ncbi.nlm.nih.gov/pubmed/32095453 http://dx.doi.org/10.12793/tcp.2017.25.1.10

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