The Sole Mycobacterium smegmatis MazF Toxin Targets tRNA(Lys) to Impart Highly Selective, Codon-Dependent Proteome Reprogramming

Survival of mycobacteria, both free-living and host-dependent pathogenic species, is dependent on their ability to evade being killed by the stresses they routinely encounter. Toxin-antitoxin (TA) systems are unique to bacteria and archaea and are thought to function as stress survival proteins. Her...

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Detalles Bibliográficos
Autores principales: Barth, Valdir Cristovao, Woychik, Nancy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033543/
https://www.ncbi.nlm.nih.gov/pubmed/32117414
http://dx.doi.org/10.3389/fgene.2019.01356