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lncRNA CISAL Inhibits BRCA1 Transcription by Forming a Tertiary Structure at Its Promoter

Cisplatin-based neoadjuvant chemotherapy has been shown to improve survival in patients with squamous cell carcinoma (SCC), but clinical biomarkers to predict chemosensitivity remain elusive. Here, we show the long noncoding RNA (lncRNA) LINC01011, which we termed cisplatin-sensitivity-associated ln...

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Detalles Bibliográficos
Autores principales: Fan, Song, Tian, Tian, Lv, Xiaobin, Lei, Xinyuan, Yang, Zhaohui, Liu, Mo, Liang, Faya, Li, Shunrong, Lin, Xiaofeng, Lin, Zhaoyu, Xie, Shule, Li, Bowen, Chen, Weixiong, Pan, Guokai, Lin, Xinyu, Ou, Zhanpeng, Zhang, Yin, Peng, Yu, Xiao, Liping, Zhang, Lizao, Sun, Sheng, Zhang, Hanqing, Lin, Sigeng, Li, Qunxing, Zeng, Binghui, Kontos, Filippos, Ruan, Yi, Ferrone, Soldano, Lin, Dechen, Tannous, Bakhos A., Li, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033639/
https://www.ncbi.nlm.nih.gov/pubmed/32000125
http://dx.doi.org/10.1016/j.isci.2020.100835