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Complex Stability and an Irrevertible Transition Reverted by Peptide and Fibroblasts in a Dynamic Model of Innate Immunity
We here apply a control analysis and various types of stability analysis to an in silico model of innate immunity that addresses the management of inflammation by a therapeutic peptide. Motivation is the observation, both in silico and in experiments, that this therapy is not robust. Our modeling re...
Autores principales: | Abudukelimu, Abulikemu, Barberis, Matteo, Redegeld, Frank, Sahin, Nilgun, Sharma, Raju P., Westerhoff, Hans V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033641/ https://www.ncbi.nlm.nih.gov/pubmed/32117197 http://dx.doi.org/10.3389/fimmu.2019.03091 |
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