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Maturation of Human Pluripotent Stem Cell-Derived Cerebellar Neurons in the Absence of Co-culture

The cerebellum plays a critical role in all vertebrates, and many neurological disorders are associated with cerebellum dysfunction. A major limitation in cerebellar research has been the lack of adequate disease models. As an alternative to animal models, cerebellar neurons differentiated from plur...

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Detalles Bibliográficos
Autores principales: Silva, Teresa P., Bekman, Evguenia P., Fernandes, Tiago G., Vaz, Sandra H., Rodrigues, Carlos A. V., Diogo, Maria Margarida, Cabral, Joaquim M. S., Carmo-Fonseca, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033648/
https://www.ncbi.nlm.nih.gov/pubmed/32117945
http://dx.doi.org/10.3389/fbioe.2020.00070