The changing role of radiation therapy in the management of oligometastatic disease

It is clear from surgical series that there are selected patients presenting with localised metastatic disease who can be cured by radical ablation of the metastasis. To date this has been limited to surgical resection but the evolution of stereotactic ablative body radiotherapy (SABR) has opened ne...

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Detalles Bibliográficos
Autores principales: Tharmalingham, H., Hoskin, P.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Short communications and technical note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033765/
https://www.ncbi.nlm.nih.gov/pubmed/32095538
http://dx.doi.org/10.1016/j.tipsro.2017.01.001
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author Tharmalingham, H.
Hoskin, P.J.
author_facet Tharmalingham, H.
Hoskin, P.J.
author_sort Tharmalingham, H.
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description It is clear from surgical series that there are selected patients presenting with localised metastatic disease who can be cured by radical ablation of the metastasis. To date this has been limited to surgical resection but the evolution of stereotactic ablative body radiotherapy (SABR) has opened new opportunities. Hypofractionated radiation delivery in 1 to 5 fractions can achieve durable local control with low toxicity. The focus is now to develop robust biomarkers so that those with true oligometastatic and thereby potentially curable disease can be selected for this approach.
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spelling pubmed-70337652020-02-24 The changing role of radiation therapy in the management of oligometastatic disease Tharmalingham, H. Hoskin, P.J. Tech Innov Patient Support Radiat Oncol Short communications and technical note It is clear from surgical series that there are selected patients presenting with localised metastatic disease who can be cured by radical ablation of the metastasis. To date this has been limited to surgical resection but the evolution of stereotactic ablative body radiotherapy (SABR) has opened new opportunities. Hypofractionated radiation delivery in 1 to 5 fractions can achieve durable local control with low toxicity. The focus is now to develop robust biomarkers so that those with true oligometastatic and thereby potentially curable disease can be selected for this approach. Elsevier 2017-02-16 /pmc/articles/PMC7033765/ /pubmed/32095538 http://dx.doi.org/10.1016/j.tipsro.2017.01.001 Text en © 2017 Published by Elsevier Ireland Ltd on behalf of European Society for Radiotherapy & Oncology. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Short communications and technical note
Tharmalingham, H.
Hoskin, P.J.
The changing role of radiation therapy in the management of oligometastatic disease
title The changing role of radiation therapy in the management of oligometastatic disease
title_full The changing role of radiation therapy in the management of oligometastatic disease
title_fullStr The changing role of radiation therapy in the management of oligometastatic disease
title_full_unstemmed The changing role of radiation therapy in the management of oligometastatic disease
title_short The changing role of radiation therapy in the management of oligometastatic disease
title_sort changing role of radiation therapy in the management of oligometastatic disease
topic Short communications and technical note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033765/
https://www.ncbi.nlm.nih.gov/pubmed/32095538
http://dx.doi.org/10.1016/j.tipsro.2017.01.001
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