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Endothelial Immune Activation by Medin: Potential Role in Cerebrovascular Disease and Reversal by Monosialoganglioside‐Containing Nanoliposomes

BACKGROUND: The function of medin, one of the most common human amyloid proteins that accumulates in the vasculature with aging, remains unknown. We aim to probe medin's role in cerebrovascular disease by comparing cerebral arterial medin content between cognitively normal and vascular dementia...

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Detalles Bibliográficos
Autores principales: Karamanova, Nina, Truran, Seth, Serrano, Geidy E., Beach, Thomas G., Madine, Jillian, Weissig, Volkmar, Davies, Hannah A., Veldhuizen, Jaimeson, Nikkhah, Mehdi, Hansen, Michael, Zhang, Weiyang, D'Souza, Karen, Franco, Daniel A., Migrino, Raymond Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033828/
https://www.ncbi.nlm.nih.gov/pubmed/31928157
http://dx.doi.org/10.1161/JAHA.119.014810