Syndecan‐4 Protects the Heart From the Profibrotic Effects of Thrombin‐Cleaved Osteopontin

BACKGROUND: Pressure overload of the heart occurs in patients with hypertension or valvular stenosis and induces cardiac fibrosis because of excessive production of extracellular matrix by activated cardiac fibroblasts. This initially provides essential mechanical support to the heart, but eventuall...

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Detalles Bibliográficos
Autores principales: Herum, Kate M., Romaine, Andreas, Wang, Ariel, Melleby, Arne Olav, Strand, Mari E., Pacheco, Julian, Braathen, Bjørn, Dunér, Pontus, Tønnessen, Theis, Lunde, Ida G., Sjaastad, Ivar, Brakebusch, Cord, McCulloch, Andrew D., Gomez, Maria F., Carlson, Cathrine R., Christensen, Geir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033859/
https://www.ncbi.nlm.nih.gov/pubmed/32000579
http://dx.doi.org/10.1161/JAHA.119.013518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033859/
https://www.ncbi.nlm.nih.gov/pubmed/32000579
http://dx.doi.org/10.1161/JAHA.119.013518

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