Cargando…

Aspirin Reduces the Potentiating Effect of CD40L on Platelet Aggregation via Inhibition of Myosin Light Chain

BACKGROUND: Antiplatelet therapy with aspirin (acetylsalicylic acid [ASA]) is less efficient in some coronary patients, which increases their risk of developing thrombosis. Elevated blood levels of thromboinflammatory mediators, like soluble CD40L (sCD40L), may explain such variabilities. We hypothe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kojok, Kevin, Mohsen, Mira, El Kadiry, Abed El Hakim, Mourad, Walid, Merhi, Yahye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033871/ https://www.ncbi.nlm.nih.gov/pubmed/32009527 http://dx.doi.org/10.1161/JAHA.119.013396

Ejemplares similares

Role of NF-κB in Platelet Function
por: Kojok, Kevin, et al.
Publicado: (2019)

CD40L Priming of Platelets via NF‐κB Activation is CD40‐ and TAK1‐Dependent
por: Kojok, Kevin, et al.
Publicado: (2018)

The Role of the Proteasome in Platelet Function
por: El-Kadiry, Abed El-Hakim, et al.
Publicado: (2021)

Bone marrow aspirate concentrate versus platelet-rich plasma for treating knee osteoarthritis: a one-year non-randomized retrospective comparative study
por: El-Kadiry, Abed El-Hakim, et al.
Publicado: (2022)

Implication of Platelets in Immuno-Thrombosis and Thrombo-Inflammation
por: Zaid, Younes, et al.
Publicado: (2022)

Effects of Myosin “Essential” Light Chain A1 on the Aggregation Properties of the Myosin Head
por: Markov, D.I., et al.
Publicado: (2010)

Attenuated platelet aggregation in patients with septic shock is independent from the activity state of myosin light chain phosphorylation or a reduction in Rho kinase-dependent inhibition of myosin light chain phosphatase
por: Reddi, Benjamin AJ, et al.
Publicado: (2015)

Early outgrowth cells versus endothelial colony forming cells functions in platelet aggregation
por: Bou Khzam, Lara, et al.
Publicado: (2015)

Cell Therapy: Types, Regulation, and Clinical Benefits
por: El-Kadiry, Abed El-Hakim, et al.
Publicado: (2021)

CD154: the atherosclerotic risk factor in rheumatoid arthritis?
por: Hassan, Ghada S, et al.
Publicado: (2013)

Mesenchymal Stem Cells Beyond Regenerative Medicine
por: Shammaa, Riam, et al.
Publicado: (2020)

Autologous BMAC Therapy Improves Spinal Degenerative Joint Disease in Lower Back Pain Patients
por: El-Kadiry, Abed El-Hakim, et al.
Publicado: (2021)

Accum™ Technology: A Novel Conjugable Primer for Onco-Immunotherapy
por: El-Kadiry, Abed El-Hakim, et al.
Publicado: (2022)

Thermal Denaturation and Aggregation of Myosin Subfragment 1 Isoforms with Different Essential Light Chains
por: Markov, Denis I., et al.
Publicado: (2010)

Myosin light chain kinase and myosin light chain phosphatase from Dictyostelium: effects of reversible phosphorylation on myosin structure and function
Publicado: (1987)

Dissecting Platelet’s Role in Viral Infection: A Double-Edged Effector of the Immune System
por: El Filaly, Hajar, et al.
Publicado: (2023)

Microelectromechanical System Measurement of Platelet Contraction: Direct Interrogation of Myosin Light Chain Phosphorylation
por: George, Mitchell J., et al.
Publicado: (2021)

Endothelial progenitor cells inhibit platelet function in a P-selectin-dependent manner
por: Abou-Saleh, Haissam, et al.
Publicado: (2015)

Fibrin Clot Structure and Platelet Aggregation in Patients with Aspirin Treatment Failure
por: Neergaard-Petersen, Søs, et al.
Publicado: (2013)

Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I
por: Sevrieva, Ivanka R., et al.
Publicado: (2020)

Prospective Evaluation of Genetic Variation in Platelet Endothelial Aggregation Receptor 1 Reveals Aspirin‐Dependent Effects on Platelet Aggregation Pathways
por: Backman, JD, et al.
Publicado: (2017)

Phosphorylation of myosin regulatory light chain controls myosin head conformation in cardiac muscle
por: Kampourakis, Thomas, et al.
Publicado: (2015)

Thirteen is enough: the myosins of Dictyostelium discoideum and their light chains
por: Kollmar, Martin
Publicado: (2006)

Synthesis of myosin heavy and light chains in muscle cultures
Publicado: (1975)

Thymoproteasome-Expressing Mesenchymal Stromal Cells Confer Protective Anti-Tumor Immunity via Cross-Priming of Endogenous Dendritic Cells
por: Bikorimana, Jean-Pierre, et al.
Publicado: (2021)

Effects of colchicine on platelet aggregation in patients on dual antiplatelet therapy with aspirin and clopidogrel
por: Cirillo, Plinio, et al.
Publicado: (2020)

The Synergistic Effect of Ginkgo biloba Extract 50 and Aspirin Against Platelet Aggregation
por: Ke, Jia, et al.
Publicado: (2021)

The Contribution of CD40/CD40L Axis in Inflammatory Bowel Disease: An Update
por: Senhaji, Nezha, et al.
Publicado: (2015)

Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin
por: Hitsumoto, Tatsuro, et al.
Publicado: (2023)

Soluble CD40 Ligand Stimulates the Pro-Angiogenic Function of Peripheral Blood Angiogenic Outgrowth Cells via Increased Release of Matrix Metalloproteinase-9
por: Bou Khzam, Lara, et al.
Publicado: (2013)

Myosin‑II heavy chain and formin mediate the targeting of myosin essential light chain to the division site before and during cytokinesis
por: Feng, Zhonghui, et al.
Publicado: (2015)

Myosin light-chain expression during avian muscle development
por: Crow, MT, et al.
Publicado: (1983)

Apoptotic Membrane Blebbing Is Regulated by Myosin Light Chain Phosphorylation
por: Mills, Jason C., et al.
Publicado: (1998)

Hybrids of Physarum myosin light chains and desensitized scallop myofibrils
Publicado: (1981)

Characteristics of light chains of Chara myosin revealed by immunological investigation
por: KAKEI, Toshihito, et al.
Publicado: (2012)

Dynamic Regulation of Myosin Light Chain Phosphorylation by Rho-kinase
por: Kaneko-Kawano, Takako, et al.
Publicado: (2012)

Myosin light chains: Teaching old dogs new tricks
por: Heissler, Sarah M, et al.
Publicado: (2015)

Ardipusilloside-I stimulates gastrointestinal motility and phosphorylation of smooth muscle myosin by myosin light chain kinase
por: Xu, Zhili, et al.
Publicado: (2017)

Comparison of Triple Anti-Platelet Therapy (Aspirin, Clopidogrel, and Cilostazol) and Double Anti-Platelet Therapy (Aspirin and Clopidogrel) on Platelet Aggregation in Type 2 Diabetic Patients Undergoing Drug-Eluting Stent Implantation
por: Yang, Tae-Hyun, et al.
Publicado: (2009)

The automation of routine light transmission platelet aggregation
por: Lawrie, A S, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_9h3gotordp9mdjhq819n8ovv88