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On the High Sensitivity of Corrosion Resistance of NiTi Stents with Respect to Inclusions: An Experimental Evidence

[Image: see text] In this study, the electrochemical breakdown potentials (E(b)) of NiTi stents were assessed in correlation to their nonmetallic inclusion fractions in the extra low inclusion (ELI) range (inclu.% < 1% in area fraction, average size <39 μm). Quantitative investigations were pe...

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Autores principales: Sun, Fan, Jordan, Laurence, Albin, Valérie, Lair, Virginie, Ringuedé, Armelle, Prima, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033967/
https://www.ncbi.nlm.nih.gov/pubmed/32095730
http://dx.doi.org/10.1021/acsomega.9b04312
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author Sun, Fan
Jordan, Laurence
Albin, Valérie
Lair, Virginie
Ringuedé, Armelle
Prima, Frédéric
author_facet Sun, Fan
Jordan, Laurence
Albin, Valérie
Lair, Virginie
Ringuedé, Armelle
Prima, Frédéric
author_sort Sun, Fan
collection PubMed
description [Image: see text] In this study, the electrochemical breakdown potentials (E(b)) of NiTi stents were assessed in correlation to their nonmetallic inclusion fractions in the extra low inclusion (ELI) range (inclu.% < 1% in area fraction, average size <39 μm). Quantitative investigations were performed to study the role of nonmetallic inclusions during pitting corrosion. Two stent samples with different inclusion fractions were fabricated using commercial NiTi tubes for studying the corrosion and mechanism. A survey of seven commercial stents in Europe was also conducted. Dependence was observed between the breakdown potentials and the inclusion fractions in the ELI stent (inclu.% = 0.2–0.8%), in which the breakdown potentials were found to be inversely proportional to inclusion fractions and densities (E(b) dropped from ∼800 to ∼400 mV). No breakdown occurred on the samples using high-purity NiTi materials (inclu.% < 0.1%). The roles of inclusions in pitting mechanisms were investigated using scanning electron microscopy (SEM) characterizations. The microstructural evidence showed that the impact of TiC and Ti(2)NiO(x) was very different in the pitting process. A maximum inclu.% ≤ 0.9% was required for obtaining E(b) ≥ 600 mV to meet the Food and Drug Administrations (FDA’s) in vivo safety acceptance (low risk up to 6 months postimplantation). The high-purity stents (inclu.% < 0.1%) did not exhibit corrosion susceptibility until 1000 mV, suggesting superior corrosion resistance and thus long-term in vivo safety.
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spelling pubmed-70339672020-02-24 On the High Sensitivity of Corrosion Resistance of NiTi Stents with Respect to Inclusions: An Experimental Evidence Sun, Fan Jordan, Laurence Albin, Valérie Lair, Virginie Ringuedé, Armelle Prima, Frédéric ACS Omega [Image: see text] In this study, the electrochemical breakdown potentials (E(b)) of NiTi stents were assessed in correlation to their nonmetallic inclusion fractions in the extra low inclusion (ELI) range (inclu.% < 1% in area fraction, average size <39 μm). Quantitative investigations were performed to study the role of nonmetallic inclusions during pitting corrosion. Two stent samples with different inclusion fractions were fabricated using commercial NiTi tubes for studying the corrosion and mechanism. A survey of seven commercial stents in Europe was also conducted. Dependence was observed between the breakdown potentials and the inclusion fractions in the ELI stent (inclu.% = 0.2–0.8%), in which the breakdown potentials were found to be inversely proportional to inclusion fractions and densities (E(b) dropped from ∼800 to ∼400 mV). No breakdown occurred on the samples using high-purity NiTi materials (inclu.% < 0.1%). The roles of inclusions in pitting mechanisms were investigated using scanning electron microscopy (SEM) characterizations. The microstructural evidence showed that the impact of TiC and Ti(2)NiO(x) was very different in the pitting process. A maximum inclu.% ≤ 0.9% was required for obtaining E(b) ≥ 600 mV to meet the Food and Drug Administrations (FDA’s) in vivo safety acceptance (low risk up to 6 months postimplantation). The high-purity stents (inclu.% < 0.1%) did not exhibit corrosion susceptibility until 1000 mV, suggesting superior corrosion resistance and thus long-term in vivo safety. American Chemical Society 2020-02-10 /pmc/articles/PMC7033967/ /pubmed/32095730 http://dx.doi.org/10.1021/acsomega.9b04312 Text en Copyright © 2020 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Sun, Fan
Jordan, Laurence
Albin, Valérie
Lair, Virginie
Ringuedé, Armelle
Prima, Frédéric
On the High Sensitivity of Corrosion Resistance of NiTi Stents with Respect to Inclusions: An Experimental Evidence
title On the High Sensitivity of Corrosion Resistance of NiTi Stents with Respect to Inclusions: An Experimental Evidence
title_full On the High Sensitivity of Corrosion Resistance of NiTi Stents with Respect to Inclusions: An Experimental Evidence
title_fullStr On the High Sensitivity of Corrosion Resistance of NiTi Stents with Respect to Inclusions: An Experimental Evidence
title_full_unstemmed On the High Sensitivity of Corrosion Resistance of NiTi Stents with Respect to Inclusions: An Experimental Evidence
title_short On the High Sensitivity of Corrosion Resistance of NiTi Stents with Respect to Inclusions: An Experimental Evidence
title_sort on the high sensitivity of corrosion resistance of niti stents with respect to inclusions: an experimental evidence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033967/
https://www.ncbi.nlm.nih.gov/pubmed/32095730
http://dx.doi.org/10.1021/acsomega.9b04312
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