Aspartic peptidase of Phialophora verrucosa as target of HIV peptidase inhibitors: blockage of its enzymatic activity and interference with fungal growth and macrophage interaction

Phialophora verrucosa causes several fungal human diseases, mainly chromoblastomycosis, which is extremely difficult to treat. Several studies have shown that human immunodeficiency virus peptidase inhibitors (HIV-PIs) are attractive candidates for antifungal therapies. This work focused on studying...

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Detalles Bibliográficos
Autores principales: Granato, Marcela Q., Sousa, Ingrid S., Rosa, Thabatta L. S. A., Gonçalves, Diego S., Seabra, Sergio H., Alviano, Daniela S., Pessolani, Maria C. V., Santos, André L. S., Kneipp, Lucimar F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034032/
https://www.ncbi.nlm.nih.gov/pubmed/32037904
http://dx.doi.org/10.1080/14756366.2020.1724994

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