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Identification of pyrvinium pamoate as an anti-tuberculosis agent in vitro and in vivo by SOSA approach amongst known drugs

Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb) bacteria, is a leading infectious cause of mortality worldwide. The emergence of drug-resistant M. tb has made control of TB more difficult. The selective optimization of side activities (SOSA) approach uses old drugs for new pharmacolog...

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Detalles Bibliográficos
Autores principales: Guan, Qing, Zhan, Lingjun, Liu, Zhi-Hao, Pan, Qin, Chen, Xu-Lin, Xiao, Zhen, Qin, Chuan, Zhang, Xiao-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034053/
https://www.ncbi.nlm.nih.gov/pubmed/32013776
http://dx.doi.org/10.1080/22221751.2020.1720527