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Synthesis of novel, DNA binding heterocyclic dehydroabietylamine derivatives as potential antiproliferative and apoptosis-inducing agents

Several dehydroabietylamine derivatives containing heterocyclic moieties such as thiophene and pyrazine ring were successfully synthesized. The antiproliferative activities of these thiophene-based Schiff-bases, thiophene amides, and pyrazine amides were investigated in vitro against Hela (cervix),...

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Detalles Bibliográficos
Autores principales: Zhao, Fengyi, Sun, Xu, Lu, Wen, Xu, Li, Shi, Jiuzhou, Yang, Shilong, Zhou, Mengyi, Su, Fan, Lin, Feng, Cao, Fuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034089/
https://www.ncbi.nlm.nih.gov/pubmed/31984809
http://dx.doi.org/10.1080/10717544.2020.1716879