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Drug-interactive mPEG-b-PLA-Phe(Boc) micelles enhance the tolerance and anti-tumor efficacy of docetaxel
Docetaxel (DTX) is one of the most promising chemotherapeutic agents for a variety of solid tumors. However, the clinical efficacy of the marketed formulation, Taxotere(®), is limited due to its poor aqueous solubility, side effects caused by the emulsifier, and low selective DTX distribution in viv...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034090/ https://www.ncbi.nlm.nih.gov/pubmed/32003299 http://dx.doi.org/10.1080/10717544.2020.1718245 |