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Physicochemical properties of Arenga pinnata Merr. endosperm and its antidiabetic activity for nutraceutical application

This study aims to provide information on physicochemical properties of Arenga pinnata endosperm (APE) and its antidiabetic activity for utilization in the food and pharmaceutical industries. The antidiabetic effect of APE was studied through an observational experiment on the blood glucose level of...

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Autores principales: Tarigan, Juliati Br., Barus, Diana A., Dalimunthe, Aminah, Perangin-Angin, Sabarmin, Nguyen, Trung T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034176/
https://www.ncbi.nlm.nih.gov/pubmed/32154151
http://dx.doi.org/10.4103/japtr.JAPTR_91_19
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author Tarigan, Juliati Br.
Barus, Diana A.
Dalimunthe, Aminah
Perangin-Angin, Sabarmin
Nguyen, Trung T.
author_facet Tarigan, Juliati Br.
Barus, Diana A.
Dalimunthe, Aminah
Perangin-Angin, Sabarmin
Nguyen, Trung T.
author_sort Tarigan, Juliati Br.
collection PubMed
description This study aims to provide information on physicochemical properties of Arenga pinnata endosperm (APE) and its antidiabetic activity for utilization in the food and pharmaceutical industries. The antidiabetic effect of APE was studied through an observational experiment on the blood glucose level of rats. The physicochemical properties of APE were determined using a texturometer, X-ray powder diffraction, Brookfield viscometer, scanning electron microscopy, Fourier-transform infrared spectroscopy, and light microscope. The APE was categorized based on its texture into three groups. The crystal structure of APE is microspore and amorf while the hydrogel has a non-Newtonian property and is stable at 50°C. The viscosity index was increased in the increasing temperature with the order of high viscosity of APE being 1, 2, and 3. The hydrogel shape of APE 1 and 3 was lameral in the concentration of 1.25%. For antidiabetic study, the findings demonstrated that the APE could reduce the blood glucose level. The APE powders 1 and 2 with the respective weight of 50 and 200 mg have significant effects on reducing rat blood glucose level compared to the diabetic rats. Based on these properties, APE could potentially be used as a natural antidiabetic food without having any side effect and in the pharmaceutical industry for some purposes.
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spelling pubmed-70341762020-03-09 Physicochemical properties of Arenga pinnata Merr. endosperm and its antidiabetic activity for nutraceutical application Tarigan, Juliati Br. Barus, Diana A. Dalimunthe, Aminah Perangin-Angin, Sabarmin Nguyen, Trung T. J Adv Pharm Technol Res Original Article This study aims to provide information on physicochemical properties of Arenga pinnata endosperm (APE) and its antidiabetic activity for utilization in the food and pharmaceutical industries. The antidiabetic effect of APE was studied through an observational experiment on the blood glucose level of rats. The physicochemical properties of APE were determined using a texturometer, X-ray powder diffraction, Brookfield viscometer, scanning electron microscopy, Fourier-transform infrared spectroscopy, and light microscope. The APE was categorized based on its texture into three groups. The crystal structure of APE is microspore and amorf while the hydrogel has a non-Newtonian property and is stable at 50°C. The viscosity index was increased in the increasing temperature with the order of high viscosity of APE being 1, 2, and 3. The hydrogel shape of APE 1 and 3 was lameral in the concentration of 1.25%. For antidiabetic study, the findings demonstrated that the APE could reduce the blood glucose level. The APE powders 1 and 2 with the respective weight of 50 and 200 mg have significant effects on reducing rat blood glucose level compared to the diabetic rats. Based on these properties, APE could potentially be used as a natural antidiabetic food without having any side effect and in the pharmaceutical industry for some purposes. Wolters Kluwer - Medknow 2020 /pmc/articles/PMC7034176/ /pubmed/32154151 http://dx.doi.org/10.4103/japtr.JAPTR_91_19 Text en Copyright: © 2020 Journal of Advanced Pharmaceutical Technology & Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Tarigan, Juliati Br.
Barus, Diana A.
Dalimunthe, Aminah
Perangin-Angin, Sabarmin
Nguyen, Trung T.
Physicochemical properties of Arenga pinnata Merr. endosperm and its antidiabetic activity for nutraceutical application
title Physicochemical properties of Arenga pinnata Merr. endosperm and its antidiabetic activity for nutraceutical application
title_full Physicochemical properties of Arenga pinnata Merr. endosperm and its antidiabetic activity for nutraceutical application
title_fullStr Physicochemical properties of Arenga pinnata Merr. endosperm and its antidiabetic activity for nutraceutical application
title_full_unstemmed Physicochemical properties of Arenga pinnata Merr. endosperm and its antidiabetic activity for nutraceutical application
title_short Physicochemical properties of Arenga pinnata Merr. endosperm and its antidiabetic activity for nutraceutical application
title_sort physicochemical properties of arenga pinnata merr. endosperm and its antidiabetic activity for nutraceutical application
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034176/
https://www.ncbi.nlm.nih.gov/pubmed/32154151
http://dx.doi.org/10.4103/japtr.JAPTR_91_19
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