Proprotein convertase 1/3-mediated down-regulation of brain-derived neurotrophic factor in cortical neurons induced by oxygen-glucose deprivation

Brain-derived neurotrophic factor (BDNF) has robust effects on synaptogenesis, neuronal differentiation and synaptic transmission and plasticity. The maturation of BDNF is a complex process. Proprotein convertase 1/3 (PC1/3) has a key role in the cleavage of protein precursors that are directed to r...

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Detalles Bibliográficos
Autores principales: Zhang, Xiang-Yang, Liu, Feng, Chen, Yan, Guo, Wei-Chun, Zhang, Zhao-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034267/
https://www.ncbi.nlm.nih.gov/pubmed/31823886
http://dx.doi.org/10.4103/1673-5374.270314

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