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Circulating ceramide ratios and risk of vascular brain aging and dementia

BACKGROUND: We determined the association between ratios of plasma ceramide species of differing fatty‐acyl chain lengths and incident dementia and Alzheimer’s disease (AD) dementia in a large, community‐based sample. METHODS: We measured plasma ceramide levels in 1892 [54% women, mean age 70.1 (SD...

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Detalles Bibliográficos
Autores principales: McGrath, Emer R., Himali, Jayandra J., Xanthakis, Vanessa, Duncan, Meredith S., Schaffer, Jean E., Ory, Daniel S., Peterson, Linda R., DeCarli, Charles, Pase, Matthew P., Satizabal, Claudia L., Vasan, Ramachandran S., Beiser, Alexa S., Seshadri, Sudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034495/
https://www.ncbi.nlm.nih.gov/pubmed/31950603
http://dx.doi.org/10.1002/acn3.50973