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Comparison of the GPVI inhibitors losartan and honokiol
Losartan and honokiol are small molecules which have been described to inhibit aggregation of platelets by collagen. Losartan has been proposed to block clustering of GPVI but not to affect binding of collagen. Honokiol has been reported to bind directly to GPVI but only at a concentration that is t...
Autores principales: | Onselaer, Marie-Blanche, Nagy, Magdolna, Pallini, Chiara, Pike, Jeremy A, Perrella, Gina, Quintanilla, Lourdes Garcia, Eble, Johannes A, Poulter, Natalie S., Heemskerk, Johan W.M., Watson, Steve P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034533/ https://www.ncbi.nlm.nih.gov/pubmed/30849265 http://dx.doi.org/10.1080/09537104.2019.1585526 |
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