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Wide resection of soft tissue sarcomas after unplanned primary procedures: A long-term follow-up study

Unplanned resection of soft-tissue sarcomas (STS) predispose the patients to recurrences and metastases, secondary wide resection is usually warranted. To investigate the outcomes of re-excision of STS after unplanned initial resection. The records of 39 patients undergoing re-excision of STS after...

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Autores principales: Kang, Jian, Xu, Ming, Wang, Bing, Yu, Xiuchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034676/
https://www.ncbi.nlm.nih.gov/pubmed/32080080
http://dx.doi.org/10.1097/MD.0000000000019067
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author Kang, Jian
Xu, Ming
Wang, Bing
Yu, Xiuchun
author_facet Kang, Jian
Xu, Ming
Wang, Bing
Yu, Xiuchun
author_sort Kang, Jian
collection PubMed
description Unplanned resection of soft-tissue sarcomas (STS) predispose the patients to recurrences and metastases, secondary wide resection is usually warranted. To investigate the outcomes of re-excision of STS after unplanned initial resection. The records of 39 patients undergoing re-excision of STS after unplanned initial resection from January 2006 through December 2015 were retrospectively investigated. There were 17 males and 22 females, the mean age was 45.7 years. Most initial unplanned resections were performed in rural hospitals by surgeons from general surgery department, dermatology department, plastic surgery department, and orthopedic department. Thirty-five patients underwent secondary wide resections in our department. Histopathological findings indicated positive margins after primary surgeries in 18 patients. Until the conclusion of 37.2-month follow-up, 7 patients developed metastasis, 3 had local recurrence, and 7 were dead. Positive margins were associated with increased metastases and lower survival rates (P < .05). There was no significant difference in recurrences between the 2 groups. Unplanned initial resection of STS often lead to unfavorable prognosis. Primary wide resections are warranted for this disease entity.
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spelling pubmed-70346762020-03-10 Wide resection of soft tissue sarcomas after unplanned primary procedures: A long-term follow-up study Kang, Jian Xu, Ming Wang, Bing Yu, Xiuchun Medicine (Baltimore) 5700 Unplanned resection of soft-tissue sarcomas (STS) predispose the patients to recurrences and metastases, secondary wide resection is usually warranted. To investigate the outcomes of re-excision of STS after unplanned initial resection. The records of 39 patients undergoing re-excision of STS after unplanned initial resection from January 2006 through December 2015 were retrospectively investigated. There were 17 males and 22 females, the mean age was 45.7 years. Most initial unplanned resections were performed in rural hospitals by surgeons from general surgery department, dermatology department, plastic surgery department, and orthopedic department. Thirty-five patients underwent secondary wide resections in our department. Histopathological findings indicated positive margins after primary surgeries in 18 patients. Until the conclusion of 37.2-month follow-up, 7 patients developed metastasis, 3 had local recurrence, and 7 were dead. Positive margins were associated with increased metastases and lower survival rates (P < .05). There was no significant difference in recurrences between the 2 groups. Unplanned initial resection of STS often lead to unfavorable prognosis. Primary wide resections are warranted for this disease entity. Wolters Kluwer Health 2020-02-21 /pmc/articles/PMC7034676/ /pubmed/32080080 http://dx.doi.org/10.1097/MD.0000000000019067 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 5700
Kang, Jian
Xu, Ming
Wang, Bing
Yu, Xiuchun
Wide resection of soft tissue sarcomas after unplanned primary procedures: A long-term follow-up study
title Wide resection of soft tissue sarcomas after unplanned primary procedures: A long-term follow-up study
title_full Wide resection of soft tissue sarcomas after unplanned primary procedures: A long-term follow-up study
title_fullStr Wide resection of soft tissue sarcomas after unplanned primary procedures: A long-term follow-up study
title_full_unstemmed Wide resection of soft tissue sarcomas after unplanned primary procedures: A long-term follow-up study
title_short Wide resection of soft tissue sarcomas after unplanned primary procedures: A long-term follow-up study
title_sort wide resection of soft tissue sarcomas after unplanned primary procedures: a long-term follow-up study
topic 5700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034676/
https://www.ncbi.nlm.nih.gov/pubmed/32080080
http://dx.doi.org/10.1097/MD.0000000000019067
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