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A rare clinical entity as large intrarenal abscess in a typeII diabetic patient due to Candida tropicalis: Case report

BACKGROUND AND PURPOSE: Fungal renal abscesses are rare entities associated with significant morbidity and mortality. Affected kidneys can have microabscess, pyelonephritis, pyonephrosis, or papillary necrosis. CASE REPORT: Herein, we reported an unusual case of a large renal abscess cause by Candid...

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Autores principales: Chandra, Abhilash, Rao, Namrata, Das, Anupam, Sen, Manodeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society of Medical Mycology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034790/
https://www.ncbi.nlm.nih.gov/pubmed/32104745
http://dx.doi.org/10.18502/cmm.5.4.2150
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author Chandra, Abhilash
Rao, Namrata
Das, Anupam
Sen, Manodeep
author_facet Chandra, Abhilash
Rao, Namrata
Das, Anupam
Sen, Manodeep
author_sort Chandra, Abhilash
collection PubMed
description BACKGROUND AND PURPOSE: Fungal renal abscesses are rare entities associated with significant morbidity and mortality. Affected kidneys can have microabscess, pyelonephritis, pyonephrosis, or papillary necrosis. CASE REPORT: Herein, we reported an unusual case of a large renal abscess cause by Candida tropicalis in a diabetic patient. The entity presented as a lump in the abdomen and later was diagnosed to be an abscess on computed tomography scan. Candida tropicalis was confirmed on the culture of the aspirate. The abscess was successfully treated by percutaneous drainage and administration of amphotericin B deoxycholate. CONCLUSION: Candida tropicalis is now a global concern because of its rising prevalence and high virulence. The growing resistance of this Candida species to azoles, as in our case, calls for a more judicious usage of antifungal agents. Empirical therapy with either amphotericin or echinocandins is an option in case of high azole resistance. This case highlights the importance of timely diagnosis and implementation of aggressive management in cases suffering from fungal abscesses.
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spelling pubmed-70347902020-02-26 A rare clinical entity as large intrarenal abscess in a typeII diabetic patient due to Candida tropicalis: Case report Chandra, Abhilash Rao, Namrata Das, Anupam Sen, Manodeep Curr Med Mycol Case Report BACKGROUND AND PURPOSE: Fungal renal abscesses are rare entities associated with significant morbidity and mortality. Affected kidneys can have microabscess, pyelonephritis, pyonephrosis, or papillary necrosis. CASE REPORT: Herein, we reported an unusual case of a large renal abscess cause by Candida tropicalis in a diabetic patient. The entity presented as a lump in the abdomen and later was diagnosed to be an abscess on computed tomography scan. Candida tropicalis was confirmed on the culture of the aspirate. The abscess was successfully treated by percutaneous drainage and administration of amphotericin B deoxycholate. CONCLUSION: Candida tropicalis is now a global concern because of its rising prevalence and high virulence. The growing resistance of this Candida species to azoles, as in our case, calls for a more judicious usage of antifungal agents. Empirical therapy with either amphotericin or echinocandins is an option in case of high azole resistance. This case highlights the importance of timely diagnosis and implementation of aggressive management in cases suffering from fungal abscesses. Iranian Society of Medical Mycology 2019 /pmc/articles/PMC7034790/ /pubmed/32104745 http://dx.doi.org/10.18502/cmm.5.4.2150 Text en © 2019, Published by Mazandaran University of Medical Sciences on behalf of Iranian Society of Medical Mycology and Invasive Fungi Research Center. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chandra, Abhilash
Rao, Namrata
Das, Anupam
Sen, Manodeep
A rare clinical entity as large intrarenal abscess in a typeII diabetic patient due to Candida tropicalis: Case report
title A rare clinical entity as large intrarenal abscess in a typeII diabetic patient due to Candida tropicalis: Case report
title_full A rare clinical entity as large intrarenal abscess in a typeII diabetic patient due to Candida tropicalis: Case report
title_fullStr A rare clinical entity as large intrarenal abscess in a typeII diabetic patient due to Candida tropicalis: Case report
title_full_unstemmed A rare clinical entity as large intrarenal abscess in a typeII diabetic patient due to Candida tropicalis: Case report
title_short A rare clinical entity as large intrarenal abscess in a typeII diabetic patient due to Candida tropicalis: Case report
title_sort rare clinical entity as large intrarenal abscess in a typeii diabetic patient due to candida tropicalis: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034790/
https://www.ncbi.nlm.nih.gov/pubmed/32104745
http://dx.doi.org/10.18502/cmm.5.4.2150
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