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Inter-species variation in monovalent anion substrate selectivity and inhibitor sensitivity in the sodium iodide symporter (NIS)

The sodium iodide symporter (NIS) transports iodide, which is necessary for thyroid hormone production. NIS also transports other monovalent anions such as tetrafluoroborate (BF(4)(-)), pertechnetate (TcO(4)(-)), and thiocyanate (SCN(-)), and is competitively inhibited by perchlorate (ClO(4)(-)). Ho...

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Detalles Bibliográficos
Autores principales:	Concilio, Susanna C., Zhekova, Hristina R., Noskov, Sergei Y., Russell, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034854/ https://www.ncbi.nlm.nih.gov/pubmed/32084174 http://dx.doi.org/10.1371/journal.pone.0229085

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