Cargando…
Using practice effects for targeted trials or sub-group analysis in Alzheimer’s disease: How practice effects predict change over time
OBJECTIVE: To describe the presence of practice effects in persons with Alzheimer disease (AD) or mild cognitive impairment (MCI) and to evaluate how practice effects affect cognitive progression and the outcome of clinical trials. METHODS: Using data from a meta-database consisting of 18 studies in...
Autores principales: | Wang, Guoqiao, Kennedy, Richard E., Goldberg, Terry E., Fowler, Mackenzie E., Cutter, Gary R., Schneider, Lon S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034859/ https://www.ncbi.nlm.nih.gov/pubmed/32084191 http://dx.doi.org/10.1371/journal.pone.0228064 |
Ejemplares similares
-
Effect of sample size re-estimation in adaptive clinical trials for Alzheimer's disease and mild cognitive impairment
por: Wang, Guoqiao, et al.
Publicado: (2015) -
Using baseline cognitive severity for enriching Alzheimer's disease clinical trials: How does Mini-Mental State Examination predict rate of change?
por: Kennedy, Richard E., et al.
Publicado: (2015) -
Association of Concomitant Use of Cholinesterase Inhibitors or Memantine With Cognitive Decline in Alzheimer Clinical Trials: A Meta-analysis
por: Kennedy, Richard E., et al.
Publicado: (2018) -
Practice effects due to serial cognitive assessment: Implications for preclinical Alzheimer's disease randomized controlled trials
por: Goldberg, Terry E., et al.
Publicado: (2015) -
Proportional constrained longitudinal data analysis models for clinical trials in sporadic Alzheimer's disease
por: Wang, Guoqiao, et al.
Publicado: (2022)