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Analysing the Clinical Features of Pneumomediastinum Associated with Diabetic Ketoacidosis in 79 Cases

OBJECTIVE: To analyse the clinical features of pneumomediastinum associated with DKA (diabetic ketoacidosis) to improve clinicians’ understanding of the disease. METHODS: A total of 78 patients with pneumomediastinum associated with DKA were identified in the literature search, and one patient treat...

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Autores principales: Zhang, Weidong, Chen, Jingfang, Wu, Xiaoming, Chen, Luyu, Wei, Jinxing, Xue, Mingqiang, Liang, Qingzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034958/
https://www.ncbi.nlm.nih.gov/pubmed/32110073
http://dx.doi.org/10.2147/DMSO.S230799
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author Zhang, Weidong
Chen, Jingfang
Wu, Xiaoming
Chen, Luyu
Wei, Jinxing
Xue, Mingqiang
Liang, Qingzheng
author_facet Zhang, Weidong
Chen, Jingfang
Wu, Xiaoming
Chen, Luyu
Wei, Jinxing
Xue, Mingqiang
Liang, Qingzheng
author_sort Zhang, Weidong
collection PubMed
description OBJECTIVE: To analyse the clinical features of pneumomediastinum associated with DKA (diabetic ketoacidosis) to improve clinicians’ understanding of the disease. METHODS: A total of 78 patients with pneumomediastinum associated with DKA were identified in the literature search, and one patient treated in our hospital was included. The clinical features of the 79 patients were retrospectively analysed, and the pathogenesis, clinical symptoms, diagnostic methods, treatment strategies and prognoses were explored. RESULTS: All cases were confirmed by chest CT (computed tomography), and Kussmaul respiration, severe vomiting, chest pain were common symptoms. The main treatment principle was to correct acidosis and treat the primary disease. The majority of patients recovered within 1–2 weeks, and only 2 patients died. CONCLUSION: Pneumomediastinum associated with DKA is a rare disease, and it has a benign course when an early diagnosis is made and aetiological treatment is administered.
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spelling pubmed-70349582020-02-27 Analysing the Clinical Features of Pneumomediastinum Associated with Diabetic Ketoacidosis in 79 Cases Zhang, Weidong Chen, Jingfang Wu, Xiaoming Chen, Luyu Wei, Jinxing Xue, Mingqiang Liang, Qingzheng Diabetes Metab Syndr Obes Original Research OBJECTIVE: To analyse the clinical features of pneumomediastinum associated with DKA (diabetic ketoacidosis) to improve clinicians’ understanding of the disease. METHODS: A total of 78 patients with pneumomediastinum associated with DKA were identified in the literature search, and one patient treated in our hospital was included. The clinical features of the 79 patients were retrospectively analysed, and the pathogenesis, clinical symptoms, diagnostic methods, treatment strategies and prognoses were explored. RESULTS: All cases were confirmed by chest CT (computed tomography), and Kussmaul respiration, severe vomiting, chest pain were common symptoms. The main treatment principle was to correct acidosis and treat the primary disease. The majority of patients recovered within 1–2 weeks, and only 2 patients died. CONCLUSION: Pneumomediastinum associated with DKA is a rare disease, and it has a benign course when an early diagnosis is made and aetiological treatment is administered. Dove 2020-02-17 /pmc/articles/PMC7034958/ /pubmed/32110073 http://dx.doi.org/10.2147/DMSO.S230799 Text en © 2020 Zhang et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Zhang, Weidong
Chen, Jingfang
Wu, Xiaoming
Chen, Luyu
Wei, Jinxing
Xue, Mingqiang
Liang, Qingzheng
Analysing the Clinical Features of Pneumomediastinum Associated with Diabetic Ketoacidosis in 79 Cases
title Analysing the Clinical Features of Pneumomediastinum Associated with Diabetic Ketoacidosis in 79 Cases
title_full Analysing the Clinical Features of Pneumomediastinum Associated with Diabetic Ketoacidosis in 79 Cases
title_fullStr Analysing the Clinical Features of Pneumomediastinum Associated with Diabetic Ketoacidosis in 79 Cases
title_full_unstemmed Analysing the Clinical Features of Pneumomediastinum Associated with Diabetic Ketoacidosis in 79 Cases
title_short Analysing the Clinical Features of Pneumomediastinum Associated with Diabetic Ketoacidosis in 79 Cases
title_sort analysing the clinical features of pneumomediastinum associated with diabetic ketoacidosis in 79 cases
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034958/
https://www.ncbi.nlm.nih.gov/pubmed/32110073
http://dx.doi.org/10.2147/DMSO.S230799
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