Cargando…

Liquiritigenin-Loaded Submicron Emulsion Protects Against Doxorubicin-Induced Cardiotoxicity via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Activity

BACKGROUND: The clinical use of doxorubicin (DOX) is severely limited due to its cardiotoxicity. Thus, there is a need for prophylactic and treatment strategies against DOX-induced cardiotoxicity. PURPOSE: The purpose of this study was to develop a liquiritigenin-loaded submicron emulsion (Lq-SE) wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Changcan, Wu, Hongjuan, Xu, Ke, Cai, Ting, Qin, Kunming, Wu, Li, Cai, Baochang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034974/ https://www.ncbi.nlm.nih.gov/pubmed/32110010 http://dx.doi.org/10.2147/IJN.S235832

Ejemplares similares

Boesenbergia rotunda displayed anti-inflammatory, antioxidant and anti-apoptotic efficacy in doxorubicin‐induced cardiotoxicity in rats
por: Zhang, Linye, et al.
Publicado: (2023)

A Novel Submicron Emulsion System Loaded with Doxorubicin Overcome Multi-Drug Resistance in MCF-7/ADR Cells
por: Zhou, W. P., et al.
Publicado: (2015)

Cardioprotective Effects of Nanoemulsions Loaded with Anti-Inflammatory Nutraceuticals against Doxorubicin-Induced Cardiotoxicity
por: Quagliariello, Vincenzo, et al.
Publicado: (2018)

Mokko Lactone Alleviates Doxorubicin-Induced Cardiotoxicity in Rats via Antioxidant, Anti-Inflammatory, and Antiapoptotic Activities
por: Sirwi, Alaa, et al.
Publicado: (2022)

Lipid Emulsion Inhibits the Late Apoptosis/Cardiotoxicity Induced by Doxorubicin in Rat Cardiomyoblasts
por: Subbarao, Raghavendra Baregundi, et al.
Publicado: (2018)

A Systematic Review of the Potential Chemoprotective Effects of Resveratrol on Doxorubicin-Induced Cardiotoxicity: Focus on the Antioxidant, Antiapoptotic, and Anti-Inflammatory Activities
por: Hu, Li-Feng, et al.
Publicado: (2021)

Stereospecific pharmacokinetic characterization of liquiritigenin in the rat
por: Alrushaid, Samaa, et al.
Publicado: (2017)

Doxorubicin–Loaded Human Serum Albumin Submicron Particles: Preparation, Characterization and In Vitro Cellular Uptake
por: Chaiwaree, Saranya, et al.
Publicado: (2020)

The true colors of autophagy in doxorubicin-induced cardiotoxicity
por: Xiao, Bin, et al.
Publicado: (2019)

Biotransformation of Liquiritigenin into Characteristic Metabolites by the Gut Microbiota
por: Keranmu, Adili, et al.
Publicado: (2022)

Liquiritigenin Inhibits Tumor Growth and Vascularization in a Mouse Model of Hela Cells
por: Liu, Yuxin, et al.
Publicado: (2012)

Anti-Inflammatory, Anti-Apoptotic, and Antioxidant Roles of Honey, Royal Jelly, and Propolis in Suppressing Nephrotoxicity Induced by Doxorubicin in Male Albino Rats
por: Mohamed, Hanaa K., et al.
Publicado: (2022)

Ceratonia siliqua pods (Carob) methanol extract alleviates doxorubicin-induced nephrotoxicity via antioxidant, anti-inflammatory and anti-apoptotic pathways in rats
por: Atta, Attia H., et al.
Publicado: (2023)

Lady’s Bedstraw as a Powerful Antioxidant for Attenuation of Doxorubicin-Induced Cardiotoxicity
por: Bradic, Jovana, et al.
Publicado: (2023)

Pharmacological characterization of liquiritigenin, a chiral flavonoid in licorice
por: Alrushaid, Samaa, et al.
Publicado: (2016)

Exploration of Tilmicosin Cardiotoxicity in Rats and the Protecting Role of the Rhodiola rosea Extract: Potential Roles of Cytokines, Antioxidant, Apoptotic, and Anti-Fibrotic Pathways
por: Elgendy, Salwa A., et al.
Publicado: (2023)

Bibliometric and visual analysis of doxorubicin-induced cardiotoxicity
por: Lin, Xiaoxiao, et al.
Publicado: (2023)

Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin
por: Martins-Marques, Tania, et al.
Publicado: (2016)

INKing the Cardiotoxicity Out of Doxorubicin
por: Guo, Zhen, et al.
Publicado: (2023)

Low dose radiation prevents doxorubicin-induced cardiotoxicity
por: Jiang, Xin, et al.
Publicado: (2017)

Mitochondrial-Targeted Therapy for Doxorubicin-Induced Cardiotoxicity
por: Wu, Bin Bin, et al.
Publicado: (2022)

Simvastatin Reduces Doxorubicin-Induced Cardiotoxicity: Effects beyond Its Antioxidant Activity
por: Pecoraro, Michela, et al.
Publicado: (2023)

MicroRNA in the Diagnosis and Treatment of Doxorubicin-Induced Cardiotoxicity
por: Kuang, Ziyu, et al.
Publicado: (2023)

Liquiritigenin Decreases Selective Molecular and Behavioral Effects of Cocaine in Rodents
por: Jang, E. Y, et al.
Publicado: (2011)

Spectroscopic and Docking Studies on the Binding of Liquiritigenin with Hyaluronidase for Antiallergic Mechanism
por: Zeng, Hua-jin, et al.
Publicado: (2016)

UVRAG Deficiency Exacerbates Doxorubicin-Induced Cardiotoxicity
por: An, Lin, et al.
Publicado: (2017)

MicroRNA therapy confers anti-senescent effects on doxorubicin-related cardiotoxicity by intracellular and paracrine signaling
por: Xia, Wenzheng, et al.
Publicado: (2021)

Effects of Process and Formulation Parameters on Submicron Polymeric Particles Produced by a Rapid Emulsion-Diffusion Method
por: Domínguez-Delgado, Clara Luisa, et al.
Publicado: (2022)

The Gastroprotective Effect of Menthol: Involvement of Anti-Apoptotic, Antioxidant and Anti-Inflammatory Activities
por: Rozza, Ariane Leite, et al.
Publicado: (2014)

Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review
por: Xu, Yayun, et al.
Publicado: (2020)

Isorhamnetin Protects against Doxorubicin-Induced Cardiotoxicity In Vivo and In Vitro
por: Sun, Jing, et al.
Publicado: (2013)

Anti-Inflammatory Activities of Licorice Extract and Its Active Compounds, Glycyrrhizic Acid, Liquiritin and Liquiritigenin, in BV2 Cells and Mice Liver
por: Yu, Ji-Yeon, et al.
Publicado: (2015)

Role of acetylation in doxorubicin-induced cardiotoxicity
por: Li, Daisong, et al.
Publicado: (2021)

Dipyridamole ameliorates doxorubicin-induced cardiotoxicity
por: Alyasiry, Esraa, et al.
Publicado: (2022)

The role of inflammation and antioxidant defenses in the cardiotoxicity of doxorubicin in elderly CD-1 male mice
por: Reis-Mendes, Ana, et al.
Publicado: (2023)

The Calcium-Activated Chloride Channel TMEM16A is Inhibitied by Liquiritigenin
por: Kato, Mami, et al.
Publicado: (2021)

Hydrodynamic cavitation: A feasible approach to intensify the emulsion cross-linking process for chitosan nanoparticle synthesis
por: Zhang, Kunming, et al.
Publicado: (2021)

The anti-apoptotic, antioxidant and anti-inflammatory effects of curcumin on acrylamide-induced neurotoxicity in rats
por: Guo, Jie, et al.
Publicado: (2020)

Protective Role of Vitamin B(1) in Doxorubicin-Induced Cardiotoxicity in Rats: Focus on Hemodynamic, Redox, and Apoptotic Markers in Heart
por: Rankovic, Marina, et al.
Publicado: (2021)

A novel submicron emulsion system loaded with vincristine–oleic acid ion-pair complex with improved anticancer effect: in vitro and in vivo studies
por: Zhang, Ting, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_4hv1qcej321o34r7iurac6r2g7