Identification of hub genes, key pathways, and therapeutic agents in Hutchinson–Gilford Progeria syndrome using bioinformatics analysis

BACKGROUND: Hutchinson–Gilford Progeria syndrome (HGPS) is a rare lethal premature and accelerated aging disease caused by mutations in the lamin A/C gene. Nevertheless, the mechanisms of cellular damage, senescence, and accelerated aging in HGPS are not fully understood. Therefore, we aimed to scre...

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Detalles Bibliográficos
Autores principales: Wang, Dengchuan, Liu, Shengshuo, Xu, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
3500
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035007/
https://www.ncbi.nlm.nih.gov/pubmed/32049798
http://dx.doi.org/10.1097/MD.0000000000019022

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